Effect of bushen huayu composite on secretion of lymphocytic interleukin-2 and interleukin-2 receptor expression in the aged / 中国中西医结合杂志

<p><b>OBJECTIVE</b>To study the effect of Bushen Huayu Composite (BSHY) on interleukin-2 (IL-2) secretion and IL-2 receptor expression in the aged.</p><p><b>METHODS</b>IL-2 was examined by methyl thiazolyl tetrazolium (MTT) method and IL-2 dependent cellular stains, IL-2 receptor expression was examined by FACS-indirect immunofluorescence.</p><p><b>RESULTS</b>Aging could result in the decrease in lymphocytic IL-2 secretion and IL-2 receptor expression (P < 0.01, P < 0.05), which could be improved by BSHY (P < 0.01, P < 0.05).</p><p><b>CONCLUSION</b>BSHY has significant up-regulatory effect on immune function of lymphocytes in the aged.</p>